Report
From the perspective of precision nutrition and Ayurveda, we analyze what is happening inside your body at the molecular level.
Mr. Yuta Suzuki ｜ 1st Analysis (P2511009-00001)
Thank you very much, Mr. Suzuki, for requesting this precision nutrition analysis. We have carefully reviewed the blood test data, detailed dietary records, and lifestyle information you provided. At 44 years of age, you maintain a lean physique at a BMI of 19.2 while rigorously following advanced dietary protocols such as gluten-free, casein-free, and sugar-free eating — a level of health awareness and self-discipline we find truly impressive.
From the standpoint of precision nutrition, there is no such thing as a "diet that is good for everyone." Even within the standard reference ranges, your blood data shows several items with slight deviations from the precision-nutrition ideal. It is precisely within these "slight deviations" that the clues for refining your lifestyle are hidden.
In this report, we dig down to the molecular level into the drama unfolding inside your body — explaining why these symptoms occur and what genetic tendencies may lie behind them. We hope the story we are about to unravel will serve as a reliable compass for achieving your ideal of "vigorous, fulfilling days while staying ketogenic."
| Marker | Measured value | Precision-nutrition ideal | Status | Precision-nutrition interpretation |
|---|---|---|---|---|
| Triglycerides (TG) | 0.5 mmol/L approx. 44 mg/dL |
< 1.1 mmol/L | ✓ Good | Evidence of ketogenic adaptation. No insulin resistance. |
| LDL cholesterol | 5.3 mmol/L approx. 205 mg/dL |
< 3.4 mmol/L | ⚠ Monitor | Typical of LMHR (lean ketogenic). Monitor the risk of conversion to oxidized LDL. |
| HDL cholesterol | 2.19 mmol/L approx. 85 mg/dL |
> 1.3 mmol/L | ✓ Good | Very high HDL — a sign of active lipid metabolism, generally considered supportive of cardiovascular health. |
| Ferritin (stored iron) | 399 ng/mL | 100–150 ng/mL | ⚠ Monitor | A sign of chronic inflammation / oxidative stress. Increases LDL oxidation risk. |
| ALT (liver enzyme) | 18 U/L | 20–22 U/L (ideal) | △ Caution | A low value suggests functional vitamin B6 depletion. Reduced GABA / serotonin synthesis. |
| MCV (red blood cell size) | 92 fL | 85–95 fL | ✓ In range | Within normal range, but worth checking alongside B12 / folate status. |
| Total protein (TP) | 7.1 g/dL | 7.2–7.5 g/dL | △ Low | Possible malabsorption despite adequate food intake. Reduced digestive-enzyme / bile function. |
| Albumin | 4.3 g/dL | 4.5 g/dL or higher | △ Low | A practical indicator of nutritional status. Protein is not being turned into body tissue. |
| Sodium (Na) | 138 mEq/L | 140–145 mEq/L | △ Low | A sign of adrenal fatigue (HPA-axis dysregulation). Possible reduced aldosterone function. |
| Potassium (K) | 3.7 mEq/L | 4.0–5.0 mEq/L | △ Low | Adrenal / electrolyte imbalance. A state of excessive mineral excretion. |
| Blood glucose | 5.0 mmol/L 90 mg/dL |
4.4–5.3 mmol/L | ✓ Ideal | Fasting glucose is ideal. However, the possibility of nighttime hypoglycemia should be checked separately. |
| NLR (neutrophil/lymphocyte ratio) | approx. 2.46 | 1.5 or below | ⚠ High | Sympathetic dominance / chronic stress. Suppressed digestion and reduced gut immunity. |
※ The precision-nutrition ideal values differ from standard reference ranges; they are our own reference ranges for maintaining optimal mitochondrial function and neurotransmitter synthesis. They are not medical diagnostic values.
Catechol-O-methyltransferase (COMT) is the enzyme that breaks down dopamine and adrenaline. Your blood data (low ALT, electrolyte imbalance, anxiety, mid-sleep waking) suggests a Met/Met (low-activity) type, or a tendency close to it. This type excels at focus and memory, but once stress arises the breakdown of stimulatory compounds lags, so anxiety and tension tend to linger. Magnesium and B vitamins (especially folate, B12, B6) are essential for this enzyme to function.
Reduced function of methylenetetrahydrofolate reductase (MTHFR) is suspected. If folate activation (conversion to 5-MTHF) stalls, the entire methylation cycle becomes dysfunctional, affecting neurotransmitter synthesis, homocysteine metabolism, and DNA repair. Because ordinary folate supplements may not be fully utilized, direct supplementation with active folate (5-MTHF) is recommended.
The "Lean Mass Hyper-Responder (LMHR)" is a lipid profile seen in lean, active ketogenic practitioners. The triangular pattern of low TG, high LDL, and high HDL is typical. It results from active hepatic VLDL mobilization and is fundamentally different in mechanism from metabolic hyperlipidemia. However, combined with high ferritin the oxidized-LDL risk rises, so caution is warranted.
Behind the high ferritin of 399 ng/mL, we infer the influence of HFE gene variants involved in iron metabolism and inflammation-related polymorphisms. In the body, excess iron triggers the Fenton reaction, generating highly toxic hydroxyl radicals that damage mitochondria. This may be a hidden cause of chronic fatigue and reduced metabolism. Consider adjusting iron through blood donation or dietary management.
From a precision-nutrition standpoint, "eating a lot but unable to gain weight" makes us suspect "transporter dysfunction in nutrient absorption in the small intestine" or "micro-inflammation of the gut lining (leaky gut)."
In your case, although you rigorously follow gluten-free eating, a shortage of bile acids from a high-fat diet and putrefaction from undigested protein may be disrupting the balance of your gut microbiome. In particular, metabolites produced by gut bacteria (such as short-chain fatty acids) serve as the gut's energy source and maintain its barrier function.
Your current tendency toward loose stools means this barrier function has weakened and nutrients are passing straight through. To repair it, the glutamine and collagen in "bone broth," together with mucosal protection from "soluble fiber (seaweed, okra, nameko, etc.)," are highly effective. Once the gut is in order, what you eat truly becomes "body tissue," opening the path to weight gain.
High ferritin is a double-edged sword for the mitochondria, the cell's energy factories. Iron is essential for energy production, but excess iron triggers the chemical "Fenton reaction," producing highly toxic hydroxyl radicals (reactive oxygen species). These damage mitochondria and bring on fatigue and reduced metabolism.
The NAC (N-acetylcysteine) and vitamin C you take are excellent choices for countering this oxidative stress. Combining them with dietary tactics that curb excess iron absorption (such as using tannin-containing tea during and right after meals) will raise energy efficiency at the cellular level and lead to vibrant, energetic days.
| Supplement | Recommended form | Primary purpose | Timing | Status |
|---|---|---|---|---|
| Vitamin B6 (P-5-P) | Active form (pyridoxal-5-phosphate) | GABA / serotonin synthesis, ALT normalization | After breakfast & lunch | ⬆ Switch to active form |
| Active folate (5-MTHF) | Methylfolate form | Activates the methylation cycle, neurotransmitter synthesis | After breakfast | ➕ New addition |
| Magnesium | Magnesium glycinate or malate | COMT cofactor, muscle relaxation, better sleep | 30 min before bed (also with Epsom-salt bath) | ✓ Continue & strengthen |
| NAC (N-acetylcysteine) | Standard form | Glutathione production, countering oxidative stress | On an empty stomach (morning or before bed) | ✓ Continue |
| Vitamin C | Liposomal recommended (better absorption) | Adrenal support, antioxidant, ferritin management | Morning & noon (split doses) | ⬆ Switch to liposomal |
| Digestive enzymes (incl. bromelain) | Multi-enzyme | Aids protein/fat digestion, supports TP & albumin | Right before every meal | ➕ New addition |
| Taurine | Pure powder or 500mg capsule | Bile-acid support, counters loose stools, heart health | With meals | ➕ Can substitute with food |
| Vitamin B12 (methylcobalamin) | Methyl form (sublingual recommended) | Completes the methylation cycle, neuroprotection, energy production | After breakfast | ⬆ Switch to active form |
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